AICDA and B-cell chronic lymphocytic leukemia: Recent studies have revealed that various aberrant AID activities can lead to an autosomal recessive form of hyper-IgM syndrome, chronic lymphocytic leukemia (CLL) and follicular lymphoma (FL) (Revy et al., 2000 ▸; Kasar et al., 2015 ▸; Scherer et al., 2016 ▸).