FCGR2A and neoplasm: Furthermore, in the BCL1 tumor microenvironment, anti-CD27 and anti-CD20/CD27 also increased the expression of FcγRIV, a key activatory FcγR involved in mediating ADCP on murine macrophages (Hamaguchi et al., 2006, Biburger et al., 2011, Gul et al., 2014, Tipton et al., 2015a) (Figure 5C).