MCF7 and MDA-MB-231 cells secrete exosomes that induce the differentiation of adipose-derived mesenchymal stem cells into myofibroblasts, increasing their secretion of factors such as SDF-1, VEGF, CCL5, and TGFβ, which are involved in regulating tumor progression and metastasis [60]. Here, CXCL12 is linked to neoplasm.