IGF1 and folliculitis: Here, we hypothesize that the multi-herbal formulation achieves its bioactivity with possible synergistic effects from each component: (1) most importantly, induction of anagen hair regrowth (modulation of IGF-1 and TGF-β1) by HC, (2) anti-inflammatory and anti-microbial actions [28, 29] (possible protection of folliculitis) by PFVA, and (3) inhibition of 5α-reductase by GT [31, 33].