In addition to abovementioned genes, many genes that are rarely described in CKD progression were found differentially expressed in the rapid versus slow groups at T2 (e.g., LOX, PAMR1, CDCA8, C1QTNF6, FNDC1, CCDC80, MFSD7, FMO2, SI, SLC26A4). The gene discussed is LOX; the disease is chronic kidney disease.