Tumor cells derived from KrasG12D/+; p53f/f; Ng2/Cspg4+/+, and KrasG12D/+; p53f/f; Ng2/Cspg4f/f mice were treated with IGFII followed by real-time PCR analysis for Igfbp3 expression. Here, CSPG4 is linked to neoplasm.