CXCL8 and neoplasm: Indeed, oncogenic KRas is a potent inducer of various cytokines in many tumor types, including lung, where IL-8 (CXCL8) and IL-6 both contribute to lung cancer’s signature inflammatory phenotype (Ancrile et al., 2008, Campbell and Der, 2004, Ji et al., 2006, Kranenburg et al., 2004, Sparmann and Bar-Sagi, 2004, Sunaga et al., 2012).