In a study of 71 Burmese subjects with acute uncomplicated Plasmodium falciparum malaria, the individual with the CYP2A6*1/*4 genotype exhibited higher artesunate (parent) and lower dihydroatremisinin (metabolite) concentrations relative to individuals with the CYP2A6*1A/*1A, CYP2A6*1A/*1B, and CYP2A6*1B/*1B genotypes [175]. Here, CYP2A6 is linked to Plasmodium falciparum malaria.