IL1B and colitis: In a study by Lozano-Pérez et al. (2014), using a trinitrobenzenesulfonic acid model of rat colitis treated with resveratrol, myeloperoxidase activity (MPO) was decreased by the lower infiltration of neutrophils and lower levels of inflammatory markers, such as TNF-α, IL-1β, IL-6, and IL-12, in the rat colitis model [48].