BCHE and skin aging: Previous phytochemical investigations isolated plastoquinones as secondary metabolites, including sargaquinoic acid, sargahydrogquinoic acid, sargaquinal, and sargachromenol [37], which possess a wide range of biological activities, including anti-cholinesterase [26], anti-hyperproliferative disease [38], neuro-protective [39,40], photo-protective [41], anti-inflammatory [42,43,44], age-related inflammation disease and skin aging protection [45], anti-diabetic and hypolipidemic [46], anti-vascular inflammatory [19], anti-adipogenic [47], and anti-carcinogenic [48] properties.