Figure 4E shows the representative Sanger sequencing for RPGRIP1: NM_020366:exon17: c.2889delT; this mutant is absent in unaffected family individuals and unrelated 100 normal controls, including those without a family history of eye disease (wild type, depicted in Fig. 1 with pedigree III:2). The gene discussed is RPGRIP1; the disease is eye disorder.