These genes included SKP2 (Chen et al., 2011), TOP2A (Song et al., 2013), SOX4 (Jafarnejad et al., 2010), MAP2 (Soltani et al., 2005) and CTLA4 (Hannani et al., 2015), all of which have been associated with patient outcome in melanoma. Here, TOP2A is linked to melanoma.