NUDT15 and inflammatory bowel disease: Chao et al. reported that the predictive sensitivity of NUDT15 p.Arg139Cys was 49.2% in their cohort of Chinese patients with IBD but that combined analysis with Val18Ile and p.Val18_Val19insGlyVal to determine diplotypes by detecting haplotypes *5 and *6 could increase the sensitivity to 55.4% [89].