While the nonARE-containing CCL5 transcript was not affected, we observed that the ARE-containing TNFα transcript was significantly induced in the hearts of BEX1-TG mice after TAC compared with WT controls subjected to TAC, while it was significantly inhibited in the hearts of Bex1-KO mice compared with their strain-matched controls (Fig. 5g, h). This evidence concerns the gene TNF and persistent truncus arteriosus.