The cases described in this paper and in the previous studies all have reduced serum levels of THPO, whereas ordinarily THPO levels should be elevated in cases of aplastic anemia or other forms of thrombocytopenia (Dasouki et al, 2013; Pecci et al, 2018; Seo et al, 2017). The gene discussed is THPO; the disease is Thrombocytopenia.