CACNA1C and psychiatric disorder: We have observed significant sharing of CNVs across different neurodevelopmental/psychiatric diseases, impacting genes that belong to the metabotropic glutamate receptor gene networks [6, 7, 21]; CACNA1B was identified as significant in a schizophrenia case-control CNV study [4], and subsequently a close homolog, CACNA1C, was identified as significant by the PGC GWAS [3].