Busybee [34] binned several megabases of Rhodococcus sequence and a Rhodococcus plasmid with Caenorhabditis sequences including a 137,654 bp scaffold that expressed mRNA and contained a gene sequence encoding a homolog to C. elegans fibrillin-1, an extracellular matrix protein with a human homolog that results in Marfans syndrome when mutated. This evidence concerns the gene FBN1 and Marfan syndrome.