It showed that high Ezrin expression was not significantly associated with TNM stage (OR = 1.14, 95% CI = 0.66–1.97, P = 0.631) or distant metastasis (OR = 1.32, 95% CI = 0.37–4.74, P = 0.669) in esophageal cancer. Here, EZR is linked to esophageal cancer.