PRDX1 and keratoconus: To further investigate the mechanism of Prdx1 and its post-translational modifications on pERK in EL-Kras and KC mice, we evaluated levels of Prdx1/pERK and pTyr-Prdx1/pERK interactions in snap frozen pancreas lysate from 7-8 month old EL-Kras and 6 month old KC mice (Figure 5).