Consistent with reports, Sathyanarayanan A et al found that ectopic miR-145 expression or SIP1 siRNAs inhibited C33A and SiHa cell proliferation, migration and invasion, and altered the expression of EMT-associated biomarkers, and miR-145 could inhibit the expression of the SMAD-interacting protein 1 in human cervical cancer cells [22]. This evidence concerns the gene ZEB2 and cervical carcinoma.