The study revealed that cases with higher PLK1 suffered remarkably worse OS as compared to those with lower PLK1 in 10 cancer types: adrenocortical carcinoma, bladder urothelial carcinoma, breast invasive carcinoma, kidney renal clear cell carcinoma, kidney renal papillary cell carcinoma, brain lower-grade glioma, lung adenocarcinoma, pancreatic adenocarcinoma, skin cutaneous melanoma, and uterine corpus endometrial carcinoma [34]. This evidence concerns the gene PLK1 and cancer.