EGFR and epilepsy: As shown in Table 5, CNG of EGFR (HR =3.08, 95% CI =1.82-5.19, P <0.001), HER3 (HR =1.71, 95% CI =1.06-2.76, P =0.03) and HER4 (HR =1.76, 95% CI =1.08-2.87, P =0.02) was identified as independent predictors of poor patient survival with respect to ages, WHO grade, radiotherapy and epilepsy.