Although DEGs were mostly up-regulated in NK cells from SS patients under normal conditions, the down-regulated DEGs included genes in the IFN pathway, such as IRF3, TLR7, IFNA1, TLR3 and IL-12A, and the IFN-γ-inducible chemokine, CXCL10. Here, TLR3 is linked to synovial sarcoma.