We identified positive findings in most known prominent epilepsy genes such as KCNQ2 [59], CDKL5 [60], STXBP1 [61], SCN1A [62, 63], PCDH19 [64], POLG [65], SLC2A1 [66], and ARX [67] and in others more recently associated with EE such as ALG13 [56], CHD2 [68], SYNGAP1 [69], and GRIN1 [70]. The gene discussed is POLG; the disease is epilepsy.