One gene involved in free radical scavenging, SOD3, was downregulated, whereas the genes associated with cell cycle or cancer, including GADD45B, ID1, KLF10, CSRNP1, and TM4SF1, were upregulated in F. nucleatum-infected GF(P22) cells when compared to F. nucleatum-infected GF(P4) cells. The gene discussed is GADD45B; the disease is cancer.