A previous study by our group demonstrated that GTS-21 suppresses neutrophil accumulation in the kidneys following ischemia reperfusion injury [16], whereas the absence of the α7nAChR leads to exaggerated inflammatory infiltrate in the kidneys during anti-glomerular basement membrane (GBM) glomerulonephritis [49]. The gene discussed is CHRNA7; the disease is glomerulonephritis.