The male cohort without depression showed a mean CRP value of 3.07mg/L (95% CI 2.55,3.59) whilst the depressed cohort showed a mean value of 4.53mg/L (95% CI 3.47,5.60) and although both cohorts largely fall within the high risk category, the cohort with depressive symptoms are clearly at higher risk. This evidence concerns the gene CRP and depressive symptom measurement.