Transforming growth factor beta 2 (TGF-β2) has been linked to the main pathophysiologic events in glaucoma: (1) trabecular meshwork alteration by epithelial-to-mesenchymal transition resulting in rise of IOP is seen as driven by it [10], and (2) optic nerve head damage by tissue remodeling [11, 12]. This evidence concerns the gene TGFB2 and glaucoma.