Among the 15 DEGs, TX has neuroprotective effects and improves cognitive impairment by up-regulating TN-R expression, anti-inflammatory effects and inhibits diabetes by down-regulating Npy and Fcnb, anti-cancer effects by changing ribosome protein gene rps2, effects on cardiovascular disease by up-regulating Rpl17 and down-regulating robo1, and anti-oxidative activities by changing Rpl3 and Hbq1a expression. Here, TNR is linked to diabetes mellitus.