Like our study, Venn-Watson et al. (2008) further reported an episodic increase in AST and ALT with higher serum cholesterol (observed), and GGT, suggesting steatosis [59,60] and cholestasis including, autoimmune hepatitis, sclerosing cholangitis and primary biliary cirrhosis [61,62]. This evidence concerns the gene GPT and sclerosing cholangitis.