GNPDA1 and obesity due to melanocortin 4 receptor deficiency: This gene is from a family of interleukins that are frequently linked to causes of obesity-associated complications.58 The rs252111 SNP that is located in glucosamine-6-phosphate deaminase 1 (GNPDA1) has an important housekeeping function in carbohydrate derivative metabolism (Gene Ontology database).