LDLR and triple-A syndrome: As previously reported,11,14 the LDL-C–lowering alleles of rs6511720 in LDLR (OR per allele, 0.75; 95% CI, 0.67-0.83; P = 5.2 × 10−12) and rs646776 in SORT1 (OR per allele, 0.88; 95% CI, 0.82-0.94; P = 3.9 × 10−8) were strongly associated with AAA.