JMJD6 and metastatic malignant neoplasm in the lymph nodes: Remarkably, the level of JMJD6 protein expression was correlated with clinicopathologic stages (Fig. 1c), and high expression of JMJD6 was closely correlated with lymph node metastasis and distant metastasis, while no correlations were found between JMJD6 expression and gender, age, or depth of invasion (Additional file 1: Table S1).