Therefore, over the past ten years, and driven by the impulsion of the success of breakpoint cluster region-abelson (BCR-ABL) tyrosine kinase targeted therapies that are developed for Chronic Myelogenous Leukemia patients [5,6], researchers and clinicians have worked in concert for the development of specific ALK tyrosine kinase targeted therapies. The gene discussed is BCR; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.