Mice with a SCID (Severe combined immunodeficiency) mutation in the Prkdc (Protein Kinase, DNA-activated, Catalytic polypeptide) gene (Prkdcscid) on the SHO (SCID hairless outbred) genetic background are susceptible to MmuPV1 infection [121,122]. The gene discussed is PRKDC; the disease is severe combined immunodeficiency.