Endeavour ranked Ly75 (lymphocyte antigen 75) with nine nsSNPs and Itgb6 (integrin beta 6) with three nsSNPs as the top two candidate genes for Pbwg1.5 affecting resistance to obesity, and it ranked Gcg (glucagon) with one nsSNP and Grb14 (growth factor receptor-bound protein 14) with two nsSNPs as the top two candidate genes for Pbwg1.12 affecting increased body weight. The gene discussed is GCG; the disease is obesity due to melanocortin 4 receptor deficiency.