SLC22A6 and kidney disorder: Although speculative, this indicates that ciPTEC-OAT1 may be able to sufficiently produce the active form of vitamin D. In accordance with gene expression levels in uremic conditions, we found that the conversion of 25(OH)D3 was not affected by uremic toxins, suggesting a normal endocrine function of ciPTEC-OAT1 in conditions relevant to BAK applications and kidney disease.