The EMT suppressive role of PATZ1 has been also envisaged for human lung cancer, where PATZ1 expression levels are lower in lymph node metastases than in the primary tumor, and ectopic expression of PATZ1 in A549 lung cancer cells was shown to inhibit migration/invasion in vitro and invasion/colonization in vivo [43]. Here, PATZ1 is linked to lung carcinoma.