Again, besides being related to the poly-Ala expansion-driven X-linked mental retardation [258], mutations ARX are related to agenesis of the corpus callosum in females and X-linked lissencephaly with abnormal genitalia in males [259], early infantile epileptic encephalopathy-1 [260,261], Partington syndrome [261], and X-linked lissencephaly-2 [259,262]. Here, ARX is linked to Partington syndrome.