To check this possibility, we differentiated monocytes from HAM/TSP patients to DCs using GM-CSF and IL-4 in the presence of azidothymidine (AZT), and the differentiated DCs were then co-cultured with Jurkat cells stably transfected with plasmid that encodes the tandem dimer Tomato (tdTomato) under the control of the Tax responsive element (JET WT35). This evidence concerns the gene CNTN2 and tropical spastic paraparesis.