IL6 and vascular smooth muscle hypertrophy: As IL-6 has many important effects on blood vessels, including endothelial activation [62,63,64], immune cell recruitment [65,66,67,68,69,70], vascular permeability [71,72], vascular hypertrophy [73,74], and vascular fibrosis [75,76], and endothelial dysfunction [57,58] the discussion of this review will be limited to the effects of IL-6 on the vasculature (Figure 1).