In PBMCs stimulated by lipopolysaccharide (LPS) (Qin et al., 2016a), IL-6 levels were significantly correlated with CAD risk (P < 0.001), 8-OHdG levels (r = 0.318, P < 0.001), PARP activities (r = 0.516, P < 0.001), and modified Gensini scores (r = 0.226, P = 0.013), but not with vessel scores and SNP rs1136410 (Figure S2). The gene discussed is IL6; the disease is coronary artery disorder.