PARP1 and coronary artery disorder: Hence, we performed this two-stage case-control study to test whether SNP rs1136410 was associated with CAD risk, CAD severity, lipid levels, 8-hydroxy-2′-dexyguanosine (8-OHdG), interleukin (IL)-6, and PARP activities in a Chinese Han population, followed by multifactor dimensionality reduction (MDR) and classification and regression tree (CART) analyses to identify the high-order gene-environment interactions between SNP rs1136410 and traditional CAD risk factors.