BIRC5 and cancer: It is overexpressed in a variety of human neoplasms including breast [17,18], esophagus [19], stomach [20,21], colon [22], pancreas [23], bladder [24], renal cell [25], head and neck [26], oral [27], and leukemias [28], suggesting that reactivation of the survivin gene frequently occurs in cancers [29].