MTOR and angiomyolipoma: The upregulation of mammalian target of rapamycin (mTOR) signaling in angiomyolipoma cells was confirmed by WB (Supplementary Fig. 1E, F, and H), real-time reverse transcriptase-PCR (RT-PCR) (Supplementary Fig. 1G), and global transcriptomic analysis of angiomyolipoma and angiomyolipoma-derived cells vs. the corresponding normal kidney (Supplementary Fig. 2 and Supplementary Table 2).