Experimental data support the dual actions of miR205 both as a tumor suppressor by targeting ErbB3, VEGFA, ZEB1/2, etc., in breast, melanoma, renal, glioblastoma and lung cancer, and as a tumor promoter by regulating PTEN, TRAF2 and SHIP2 in breast cancer, nasopharyngeal carcinoma, and lung squamous cell carcinoma [8]. Here, PTEN is linked to neoplasm.