A more detailed study focusing on quantitative and qualitative changes in RSV-specific CD8 T cells isolated from aged BALB/c mice showed a profound decrease of immunodominant M282-90 and subdominant F85-93 and M2127-135 CD8 T responses in lung parenchyma and airways at the peak of T cell response 8 days post-infection [16]. Here, CD8A is linked to infection.