TRIM8 and neoplasm: Moreover, TRIM8 downregulation was also found in other tumours as Glioblastoma Multiforme (GBM), clear cell Renal Cell Carcinoma (ccRCC), anaplastic thyroid cancer (ATC), colorectal cancer (CRC), Chronic lymphocytic leukemia (CLL), and osteosarcoma cell lines [19,20,21,22,23,24,25,26].