Once activated, STAT3 has a broad range of biological functions, including cell activation, cell proliferation, the protection of tumour cells from apoptosis, and migration by regulating genes encoding antiapoptotic and proliferation-associated proteins, such as Bcl-xL, Mcl-1, Bcl-2, Fas, Cyclin D1, survivin, and Myc [71,72,73,74,75]. The gene discussed is STAT3; the disease is neoplasm.