They also found that IL-1β-sensitive AML samples have increased phosphorylation of p38-MAPK, and that the p38-MAPK inhibitors doramapimod (BIRB-796) or ralimetinib could inhibit the IL-1β-dependent growth of AML patient mononuclear cells or AML CD34+ cells. Here, CD34 is linked to acute myeloid leukemia.