Since CXCR3+ Tfh1 cells have been shown to be inferior to CXCR3− Tfh2/17 cells at providing help to naïve B cells, it was suggested that an influenza vaccine inducing Tfh2/17 cells rather than Tfh1 cells would be preferable (14, 41). The gene discussed is CXCR3; the disease is influenza.