NPPC and Sepsis: In accordance with prior reports from our group [26, 28], soluble urokinase plasminogen activator receptor (suPAR) and amino-terminal propeptide of C-type natriuretic peptide (NT-proCNP) were significantly elevated in patients with sepsis (median suPAR 10.7 ng/mL; median NT-proCNP 4.9 pmol/L) as compared with patients without sepsis (median suPAR 5.7 ng/mL, p < 0.001; median NT-proCNP 0.9 pmol/L, p < 0.001).